Nystatin suspension has been used since the 1950s. Patients with severe or recurrent thrush should be investigated for congenital or acquired immune deficiency. In older children, use of antibiotics or inhaled glucocorticoids is a predisposing factor for infection. Use of an infant soother increases the incidence of thrush and may make treatment less effective, unless the soother is washed carefully after use. Colonization of the mother’s nipples in breastfed infants should be considered as a potential mode of transmission. Response to antifungal agents is usually good in neonates with no major underlying condition, but a prolonged course may be required and recurrences are common. Oropharyngeal candidiasis (thrush) may start as early as seven days after birth, with an incidence in infants of 5% to 10% depending on the population studied. Īlthough mucocutaneous candidiasis is common, relatively few high-quality randomized control studies of drug therapy in immune competent hosts have been published. Systemic candidiasis is rare, but is a particular risk for premature infants. Symptomatic infections such as thrush and Candida diaper dermatitis (CDD) may develop at any age thereafter, particularly following broad-spectrum antibiotic treatment. Mucocutaneous candidiasisĬandida albicans colonization can occur as early as the first week of life. This update replaces the position statement published in 2007. The objective of the present update is to inform clinicians on options for treatment of these symptomatic but non-life-threatening fungal infections in immune-competent hosts, given the wide variety of topical, usually over-the-counter (OTC) ( Table 1), and oral prescription ( Table 2) drugs available. The most common fungal infections in infants and children are mucocutaneous candidiasis, pityriasis versicolor, tinea corporis, tinea pedis, and tinea capitis. Updated by Tobey Audcent, Michelle Barton, Karina Top Infectious Diseases and Immunization Committee Robert Bortolussi, Susanna Martin Canadian Paediatric Society.
0 Comments
Leave a Reply. |
Details
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |